We've been evaluating one Ruger's newest Mark IV rimfire semi-auto rimfire pistol, which stands on over 75 years of experience, and have the full review. 

Quick Summary: The new Ruger Mark IV 22/45, with its threaded bull barrel and factory-installed top Picatinny rail in addition to superb adjustable iron sights, is a great option for those looking for an accurate and dependable .22LR pistol that comes in well under $500.

Table of Contents

Overview
The Specs
Features
Trigger
Reliability
Accuracy
Pros & Cons
Conclusion

Overview


The Ruger Mark IV, the modern evolution of the original circa-1949 Ruger Standard (Mark I) pistol, was introduced in 2016. This updated model features a more user-friendly design, highlighted by a tool-free, one-button takedown mechanism that makes fieldstripping and cleaning significantly easier for users.

Following the release of the Mark IV, Ruger introduced the Mark IV 22/45 variant. The name "22/45" refers to the grip angle and surface controls, which closely emulate those of the famed M1911 Government pistol. Despite this design innovation, the initial 22/45 variant did not include a threaded muzzle or a top Picatinny rail. These features were reserved for the more expensive Mark IV 22/45 Tactical model, which carried a suggested retail price of $669.

Ruger has since released a bull-barreled version of the Mark IV 22/45 equipped with both a Picatinny rail and a threaded muzzle-- as featured in this review. This model is offered at a suggested price of $449, with even lower prices often available through retailers. Additional aesthetic improvements include color-matched details; the trigger and Picatinny rail both feature a stainless finish, resulting in a distinct two-toned appearance.

Thus: 
 

The bull-barreled version of the Mark IV 22/45 equipped with both a Picatinny rail and a threaded muzzle
Our review Mark IV 22/45. It has very 1911-ish overall length of 8.5 inches with an unloaded weight of 33.3 ounces. (All photos: Chris Eger/Guns.com)
The bull-barreled version of the Mark IV 22/45 equipped with both a Picatinny rail and a threaded muzzle
As teased earlier, it is both suppressor and optics-ready right out of the box. Seen equipped with a Holosun 507C sight on a Picatinny base, and a SilencerCo Switchback modular suppressor in its long format. The as-shown weight is 41 ounces. 


For full disclosure, Ruger sent Guns.com this Mark IV 22/45 for review purposes. All testing was done on this one pistol, which has been under evaluation since June 2025.
 

The Specs

  • Overall length: 8.5 inches
  • Barrel length: 4.4 inches, (0.86 wide bull profile)
  • Sight radius: 6.96 inches
  • Overall width: 1.34 inches at the widest point over the controls, upper receiver tube is 0.98 inches
  • Overall height: 5.5 inches to the top of the slide. 
  • Magazine capacity: 10+1 single-stack OEM flush fit (ships with two)
  • Trigger pull: 4.4 pounds (10-pull average) 
  • Weight, with empty OEM magazine, no optic/accessory: 33.3 ounces
  • Weight, loaded/equipped: 41 ounces ("heavy" with 10+1 rounds of CCI 40-grain Velocitor, Holosun 507C sight with Picatinny base, and SilencerCo Switchback suppressor in long format mounted)
  • Optic Footprint: 10-slot, 4.4-inch factory-installed Picatinny top rail. 

Features
 

The bull-barreled version of the Mark IV 22/45 equipped with both a Picatinny rail and a threaded muzzle
The surface controls on the left side of the frame for right-handed users include a manual safety lever (up/white for safe, down/red for fire), bolt stop, and push-button magazine release. All work ok with the exception that we found the bolt catch to be stiff. The mags drop free. 
The bull-barreled version of the Mark IV 22/45 equipped with both a Picatinny rail and a threaded muzzle
The right side of the frame sports an ambidextrous manual safety lever that can be converted to the left side only with an included washer. Speaking of safety, the pistol will not fire without a magazine inserted. Note the wide and contoured ejection port. 
The bull-barreled version of the Mark IV 22/45 equipped with both a Picatinny rail and a threaded muzzle
When it comes to grip texture and ergonomics, the Mark IV 22/45 has a familiar 1911-style grip with a serrated front strap and checkered backstrap. Note the non-slip 1911-ish double-diamond pattern on the rubber grip panels. Replacement Mark IV 22/45 panels are available in dozens of styles, including medallion wood grips, aggressive golf-ball dimpled Bogies from LOK Grips, Tandem Kross Hivegrips, etc. 
The bull-barreled version of the Mark IV 22/45 equipped with both a Picatinny rail and a threaded muzzle
The significant improvement on the Mark IV series from past models is the simple, one-button takedown to allow for quick and easy fieldstripping. Pressing a button in the back of the frame allows the barrel-receiver assembly to tilt up and off the grip frame without the use of tools. Anyone who has ever tried to field strip an older Standard or Mark II/III knows how aggravating that process was in the past. 
The bull-barreled version of the Mark IV 22/45 equipped with both a Picatinny rail and a threaded muzzle
The 4.4-inch cold hammer-forged barrel has a 0.86-inch (OD) bull profile and runs a 1:16" RH twist. 
The bull-barreled version of the Mark IV 22/45 equipped with both a Picatinny rail and a threaded muzzle
The basic components. The fixed barrel design makes straight-line chamber-to-muzzle cleaning a snap, which is important in a rimfire that you expect to run thousands of rounds of dirty lead round-nosed rounds through.
The bull-barreled version of the Mark IV 22/45 equipped with both a Picatinny rail and a threaded muzzle
Note the internal hammer and hammer spring inside the polymer grip frame. Contrary to what some may think, the Mark IV is a hammer-fired, not striker-fired, pistol, leading it to have a better trigger.
The bull-barreled version of the Mark IV 22/45 equipped with both a Picatinny rail and a threaded muzzle
Ruger stresses the internal nine-piece (including the top guide rod assembly, firing pin components and extractor spring and plunger) cylindrical bolt group ensures permanent sight-to-barrel alignment and higher accuracy potential than conventional moving-slide designs. 
The bull-barreled version of the Mark IV 22/45 equipped with both a Picatinny rail and a threaded muzzle
The pistol ships with two steel open-sided single-stack 10-round mags with easy-to-use follower buttons and a grooved foot-style baseplate moulded to fit the magwell. Of note, the Mark IV 22/45 cannot use legacy Mark III 22/45 mags. Factory replacements run about $20 a mag. 
The bull-barreled version of the Mark IV 22/45 equipped with both a Picatinny rail and a threaded muzzle
Sights are superb, with an elevation-adjustable rear and a tall, fixed front ramp. Fiberoptic and Hi-Viz replacements are readily available. 
The bull-barreled version of the Mark IV 22/45 equipped with both a Picatinny rail and a threaded muzzle
The pistol includes a 10-slot 4.4-inch factory-installed Picatinny rail for easy mounting of optics, which we used to install a Holosun 507Comp green dot on a Pic base. 
The bull-barreled version of the Mark IV 22/45 equipped with both a Picatinny rail and a threaded muzzle
The 507C has an enhanced multi-reticle system with four options, including a precision 2MOA dot, an 8MOA circle, a 20MOA circle, and a 32MOA circle, with multiple combination settings to suit individual preference. The window is big, at 1.1x0.87, and very workable. On the downside, the Pic base, added to the already high deck of the sight on the mount, voids out the rear sight. 
The bull-barreled version of the Mark IV 22/45 equipped with both a Picatinny rail and a threaded muzzle
The knurled thread protector is easy to remove in the field without tools and shows off an industry-standard 1/2x28TPI muzzle. We tested the Ruger almost exclusively with a suppressor installed, alternating between a SilencerCo Switchback and an old-school Tactical Innovations TAC65. 
The bull-barreled version of the Mark IV 22/45 equipped with both a Picatinny rail and a threaded muzzle
We paired our optic and suppressor-outfitted Ruger with a Cole Tac Varmint Wrangler Suppressed .22 Holster in Coyote Brown. Lightweight and rugged with an adjustable chest harness, it offers quick and easy access for hunters, hikers, ranchers, farmers, and, well, anyone else who looks to carry a hearing-safe semi-auto pistol in the field. All told, with the Ruger, a loaded mag and an extra mag along for the ride, including the can and glass, the holster hit the scales at just 50 ounces. 
The bull-barreled version of the Mark IV 22/45 equipped with both a Picatinny rail and a threaded muzzle
It worked with both the SiCo Switchback (top), which is configurable in four lengths, with its long 5.75-inch/7-ounce format shown. As well as my trusty old TAC65 (bottom), a super light (4-ounce) and inexpensive 6-inch aluminium can that I've had for 20 years. 
The bull-barreled version of the Mark IV 22/45 equipped with both a Picatinny rail and a threaded muzzle
Unlike some holsters that ship in from Eastern Europe, Vietnam, or Brazil, Cole Tac makes the Varmint Wrangler in its Rapid City, South Dakota shop, and it is backed by a lifetime warranty. 


Trigger


I've shot Ruger semi-auto rimfire pistols extensively over the years, going back to a circa 1950s Standard that I had as a kid. Ruger has enhanced the basic trigger in these guns several times since then, and it is decent for the price. While the current pack on our test gun ran flawlessly, it did have a fair bit of creep to it before coming to the wall, then breaking at an average of 4.4 pounds. Reset is short.

A video of the trigger in action: 
 


For those who want to crisp that trigger pull up a bit, there is no shortage of more competition-oriented Mark IV kits from Apex, Tandem Kross, and Volquartsen on the market for $120-$170. Of note, our factory trigger smoothed out a little after the first 500 rounds, so I would recommend shooting it for a while and reassessing before dropping the cash for an upgrade. 
 

Reliability


As we had lots of .22 LR on hand and this pistol is just so fun to shoot, especially when suppressed, we ran over 2,000 rounds through it with only a handful of stoppages, which we are going to chalk up to the inherent uncertainty of rimfire ammo. We didn't find a single load to choke up the gun with regularity. When compared to Umarex-made 22LR semi-auto trainers marketed under numerous brands, it is a lot more reliable. 

Most of our range ammo was bulk pack CCI Blazer 38-grain and 40-grain lead round nose. At ~$120 for a 1,500-round bucket, it's tough to beat pricewise, while still retaining high quality. We also ran several other CCI loads, Remington Golden Bullets, and some Aquila.
 

Accuracy


The Mark IV 22/45 is a plinking machine. We were easily able to do all your traditional rimfire pistolero tasks (zapping pop cans, golf balls, and empty shotgun shells) at 7-10 yards with a set of 50+ year old eyeballs and the installed iron sights. It is accurate enough that you could run it in 25m bullseye shooting, but honestly, a longer and more accurate 5.5-inch model would be better for that. 
 

The bull-barreled version of the Mark IV 22/45 equipped with both a Picatinny rail and a threaded muzzle
This is just shooting off-hand with bulk pack ammo, standing unsupported, at 15 yards with iron sights. 


Pros & Cons

Pros

Accurate
Easy to clean
Reliable
Suppressor ready
Optics ready
Tons of aftermarket support

Cons

The bolt catch is a bit stiff. 
Limited to 10-round mags

Conclusion


The Mark IV 22/45 in this format is close to being perfect when it comes to an all-around rimfire semi-auto pistol. It feels and looks good, is dependable and accurate, and just about every component has a dozen aftermarket upgrades available. We ran it with a few different cans and several different ammo loads and found it to run almost 100 percent of the time. The worst thing we can say is that it gets seriously dirty, something no 22 is immune to, and you must stay on top of that every few hundred rounds to keep it running. 

Compared to the rest of the market, this Mark IV 22/45, as reviewed, is priced right, especially for the big Pic rail on top, the threaded bull barrel, and American manufacture. Sure, guns like the SIG P322 have a significantly larger magazine capacity for about the same price, but its optics interface isn't as luxurious, you get a pencil barrel, and the aftermarket support doesn't come close to what is available for the Ruger. The closest Buckmark in features would be the Micro Bull SR, which runs significantly more than the Mark IV. 

The only problem we foresee in having one of these neat little Rugers is how often you need to buy ammo.
 

The bull-barreled version of the Mark IV 22/45 equipped with both a Picatinny rail and a threaded muzzle
The Ruger 22/45 Mark IV. 

 

revolver barrel loading graphic

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